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Besides active involvement in teaching modern biochemistry/biotechnology courses to M.Sc./Ph.D students, Prof. Owais has successfully established a small but active research group with focus on nano-particle-based novel delivery systems including dendrimers/virosomes for gene packaging and liposomes, niosomes, microspheres, solid core lipid nano-particles for vaccine delivery, gene delivery, targeted drug delivery etc; with a view to increase the efficacy and safety of encapsulated chemo-therapeutic agents/sub-unit vaccines against some important infectious diseases. The research focus of Prof. Owais group has been on: Nanoparticles based antigen/DNA vaccines against various infectious diseases with special converge on intracellular pathogens. Novel nano-carriers for targeted delivery of encapsulated therapeutic agents (siRNA/chemical compounds) for improved treatment of cancer and some imperative infectious diseases. Nanoparticles with assorted applications in the field of diagnostics, taste/odor masking and treatment of hyperbilirubinemia in model animals. A glance at some of the coveted academic achievements: National Bioscience Award-2007 by DBT, Govt. of India Rashtriya Gaurav Award-2013 Trav. Bursary Award (JAPAN)-2014 TATA Innovation Award-2013 Young Scientist Award (MYSA) -2002 Best University Teacher Award-2009 Outstanding University Researcher Award-2008 Fogarty International Fellow, NIH, (USA) Published work displayed on cover page of FEMS Immunol. Med Microbiology for all the issues of Year 2006 Published work highlighted on cover page of Molecular Medicine in May-June issue of Year 2007 Technology Transfer to Cadilla Pharmaceuticals Ltd. under PRDSF program of DST, Govt. of India Technology Transfer to Gennova Pharmaceuticals Ltd. GATE 1987, Percentile 98.89; GATE 1988, percentile 97.36 UGC-CSIR Research Fellow (JRF 1988 & JRF 1989) The article entitled as Phospholipid diversity: correlation with membrane membrane fusion events. Biochim Biophys. Acta (Biomembrane) (2005) 1669: 170-181 was categorized among top 25 by Science Direct. Another article entitled as Ethanol production from crude whey by Kluyveromyces marxianus. Biochemical Engineering Journal (2006) 27: 295-297 was categorized among top 25 by Science Direct. Best poster Award on work entitled as Escheriosome entrapped soluble blood stage antigens impart protective immunity against a multidrug resistant isolate of Plasmodium yoelii nigeriensis in BALB/c mice at Indo-Australian Conference on Biotechnology in infectious diseases at Kasturba Medical College, MAHE, Manipal. Best poster Award on work entitled as Fusogenic potential of sperm membrane lipids: Natures wisdom to accomplish targeted gene delivery at International symposium on the Predictive, Preventive and Mechanistic Mutagenesis & XXXIII EMSI annual Meeting, AMU, Aligarh during Jan 1-3, 2008. Three articles co-authored by applicant have been ranked with THREE STARS by BIOWIZARD, The Biomedical Research Portal. 1. Sharma et. al. (2006) Escheriosome entrapped soluble blood stage antigens impart protective immunity against a multi-drug resistant isolate of Plasmodium yoelii nigeriensis in BALB/c mice, Vaccine 24(7): 948-956. 2. Bajpai et. al. (2005) Concomitant delivery of tetracycline and DEC against experimental filariasis. J Drug Targetting 13(6): 375-381. 3. Mittal et. al. (2005) Expression, purification and characterization of Leishmania donovani trypanothione reductase in E. coli. Protein Expression and Purification 40: 279-286.
Nanoparticles based antigen/DNA vaccines against various infectious diseases with special converge on intracellular pathogens.